Self-Assembly From Atoms to Life

Date

October 02 to 06, 2016.

Place

Tuxtla Gutiérrez, Chiapas, México.

Organizers

Dr. Jaime Ruiz García Universidad Autónoma de San Luis Potosí (México)
Dr. Charles M. Knobler University of California Los Angeles (USA)
Dr. Alexander J. Levine University of California Los Angeles (USA)
Dr. Elías Castellano Alcantara Mesoamerican Centre for Theoretical Physics (MCTP

Sponsors

UCLA Center for Biological Physics, UCLA College of Letters and Sciences,
UCLA ICAM branch, ICAM, 12 ICAM (http://icam-i2cam.org/),
ICTP, MCTP, UNACH and CONACYT.

Speakers

  • Daan Frankel (Cambridge University, UK)
  • Arthur Evans (U. Madison)
  • Andrej Kosmrlj (Princeton)
  • Gabriel Espinosa (University of Michoacan)
  • William Jacobs (Harvard)
  • Roya Zandi (UC Riverside)
  • Ruben Cadena (UNAM)
  • Andrea Liu (UPENN)
  • Anton Souslov (Georgia Tech)
  • Eugenia Corvera (UNAM)
  • Eric Dykeman (York University, UK)
  • Rinat Goren (Weizmann Institute)
  • Laura Palomares (UNAM)
  • Joel Stavans (Weizmann Institute)
Summary

One archetypal example of emergent phenomena in nature is found in the self-assembly of complex spatio-temporal structures, either in the relaxation of many-body systems toward their thermal equilibrium or in non-equilibrium steady states characterized by continuous energy throughput. Examples of the former include crystallization and the formation of higher symmetry liquid crystalline mesophases (e.g., nematic, columnar, and semetic phases of thermotropic liquid crystals), the spontaneous formation of lipids (and multi-block copolymers) into lamellar and bicontinuous phases, in addition to cylindrical and spherical micelles, and the condensation of charged biopolymers into disordered and ordered (e.g. chiral hexatic) bundles. Recognizing the commonality of these diverse emergent phenomena, in the 1970’s researchers began to refer to this set of self-organization as “self assembly” in order to describe the phenomena of molecular and colloidal organization that result from the equilibrium assembly of many copies of one or a small number of constituents via weak (non-covalent) interactions. Fundamental questions have been explored involving the prediction of the complex equilibrium states of these systems and their low-energy excitations and linear response properties. In addition, much thought has gone into considerations of assembly kinetics and, in particular, the role of kinetic traps or glassy dynamics inhibiting the formation of thermodynamic ground state of the system. Today, researchers have shown that one may design complex pattern formers using nanofabrication techniques so that one may encode interesting or otherwise desirable complex equilibrium states into the interactions and shapes of the nanoparticles. Examples include DNA origami and pattern formation in colloids of complex shapes or with precisely controlled binding sites.

In non-equilibrium systems, such examples of complex spatio-temporal patterns abound, from patterns formed in convection to contractile waves in active contractile gels and liquid-crystal elastomers. Of course, the quintessential examples of non-equilibrium structure formation are found in biology – viral self-assembly, protein folding (and misfolding), and the dynamic organization of cytoskeletal networks provide frontier problems in statistical and biological physics today.

Program

October 03, 2016
09:00-10:00 h Self-assembly and addressable complexity
Daan Frankel (Cambridge Univ.)
PDF
10:00-11:00 h Ancient art and modern mechanics: Using origami and elasticity to design novel structures
Arthur Evans (University of Wisconsin)
PDF
11:00-11:30 h Coffee
11:30-12:30 h Complex pattern formation in solid structures induced by buckling
Andrej Kosmrlj (Princeton)
PDF
12:30-13:00 h Discussion Session I Discussion Leader:
R. Granek (Ben-Gurion Univ.)
PDF
13:00-13:40 h Inaugural Ceremony
14:30-15:30 h Shear and compression rheology of Langmuir monolayers
Gabriel Espinosa (University of Michoacan)
PDF
15:30-16:30 h Disorder induced by capillary interactions between colloidal particles at the air/water interface
Rolando Castillo (UNAM)
PDF
16:30-17:30 h Discussion Section II Discussion Leader:
Eric Raspaud (Université Paris-Sud)
18:30-19:30 h Designing new delivery materials based on viral proteins
Laura Palomares (Inst. Of Biotechnology-UNAM Cuernavaca)

October 04, 2016
09:00-10:00 h Lev Landau, Chirality, and the Assembly of Capsids
Robijn Bruinsma (UCLA)
PDF
10:00-11:00 h Features of an ancient liquid crystal world
Noel Clark (U Colorado, Boulder)
PDF
11:00-11:30 h Coffee
11:30-12:30 h Discussion Session III Discussion Leader:
M. Deserno (Carnegie Mellon Univ.)
12:30-13:30 h The assembly of small symmetric nano-shells
Roya Zandi (U California, Riverside)
PDF
14:30-15:30 h Understanding HIV-1 packaging signal by single-molecule spectroscopy
Mauricio Comas Garcia (NIH)
PDF
15:30-16:30 h CCMV capsids as nanovehicles for antimicrobial peptides
Ruben Cadena Nava (CnyN-UNAM Ensenada)
PDF
16:30-17:30 h Virus protein shell assembly beyond triangulation numbers: thermodynamics and structure
Irina Tsvetkova (Indiana)
PDF
17:30-18:30 h Discussion Section IV Discussion Leader:
R. Garmann (Harvard)
19:00-20:00 h Poster Session I

October 05, 2016
09:00-10:00 h One day in the lifetime and development of a one-dimensional organism
Joel Stavans (Weizmann Inst.)
PDF
10:00-11:00 h In vivo visualization of target location by DNA bacteriophage lambda
Rinat Goren (Weizmann Inst.)
PDF
11:30-12:30 h In vivo visualization of target location by DNA bacteriophage lambda
Andrea Liu (University of Pennsylvania)
PDF
12:30-13:30 h Discussion V Discussion Leader:
A. Evilevitch (Carnegie Mellon Univ.)
14:30-15:30 h RNA folding models for viral assembly
Eric Dykeman (York Univ.)
PDF
14:30-15:30 h Emergent collective properties of many-motor systems in one dimension
Anton Souslov (Georgia Tech.)
PDF
15:30-16:30 h Pulsatile flows: From microfluidics to the arterial network
Eugenia Corvera (UNAM)
PDF
16:30-17:30 h Discussion VI Discussion Leader:
Dan. Ou-Yang (Lehigh Univ.)
17:30-18:30 h Bill Gelbart "Summing up"
18:30-20:00 h Poster Session II
UNACH/MCTP, Ciudad Universitaria
Carretera Emiliano Zapata Km. 4,
Real del Bosque (Terán).
Tuxtla Gutiérrez, Chiapas, México.
C. P. 29050
Teléfono 52 (961) 617-80-00
Ext. 8200 y 1380
mctp@unach.mx
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